CDX2

Product Description

CDX2 is a homeobox gene that encodes an intestine-specific transcription factor.¹⁵ It is expressed in the nuclei of epithelial cells of the intestine, from duodenum to rectum. The CDX2 protein is expressed in primary and metastatic colorectal carcinomas. It has also been identified in intestinal metaplasia of the stomach and in intestinal-type gastric cancer. CDX2 is not expressed in normal gastric mucosa.^15-16

Specifications

1. Werling RW, et al. Am J Surg Pathol. 2003 Mar; 27(3):303-10.
2. Barbareschi M, et al. Am J Surg Pathol. 2003 Feb; 27(2):141-9.
3. Kim MJ. Korean Med Sci. 2005 Aug; 20(4):643-8.
4. Vang R, et al. Mod Pathol. 2006 Nov; 19(11):1421-8.
5. Raspollini ME, et al. Appl Immunohistochem Mol Morphol. 2004 Jun; 12(2):127-31.
6. Groisman GM, Meir A, Sabo E. Int J Gynecol Pathol. 2004 Jan; 23(1):52-7.